Centrosomedb - Centrosomal Proteins Database - index
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Welcome to our web site! The Holland Lab is part of the Department of Molecular Biology and Genetics at Johns Hopkins University School of Medicine. One of our central research interests is the molecular control of centriole number. Centrosome aberrations and cell cycle arrest. Cells arrest following centrosome loss and centrosome overduplication, the two conditions activating p53 by separate pathways. We are interested in how cell sense the stress and activate arrest.
During cell cycle, numerous proteins temporally and spatially localized in distinct sub-cellular regions including centrosome. Related or homolog structures in plants and budding yeast called as phragmoplast. And five animals, including. Then the integrated and searchable database M.
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Centrosomedb - Centrosomal Proteins Database - indexDESCRIPTION
Welcome to the centrosomedb database. Centrosomedb contains a set of human and fly genes encoding proteins that are localized in the centrosome, either as centrosome constituents or as centrosome visitors. Genes have been considered as centrosomal on the basis of different kinds of evidences. The domain structure of all the associated peptides. Searching with a gene name, database identifier or submmiting full text queries. Uniprot, ensembl, hgnc, entrez, ipi and refseq identifiers are supported.PARSED CONTENT
The domain centrosome.cnb.csic.es states the following, "Centrosomedb contains a set of human and fly genes encoding proteins that are localized in the centrosome, either as centrosome constituents or as centrosome visitors." I observed that the webpage stated " Genes have been considered as centrosomal on the basis of different kinds of evidences." They also stated " The domain structure of all the associated peptides. Searching with a gene name, database identifier or submmiting full text queries. Uniprot, ensembl, hgnc, entrez, ipi and refseq identifiers are supported."ANALYZE OTHER DOMAINS
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